at great expense

The new drugs, like many new cancer drugs, are monoclonal antibodies, produced from living cells at great expense.

这些新药就像许多新型抗癌药物一样，是单克隆抗体，它们是以高昂的成本用活体细胞制造的。

Fleets of vessels are despatched, at great expense, to collect the dung of petrels and penguins at the South Pole, and the incalculable element of opulence which we have on hand, we send to the sea.

我们花了大量开支，派船队到南极去收集海燕和企鹅的粪，而手边不可估量的致富因素却流入海洋。

Today, most prefab homes must be delivered at great expense on wide-load trucks that are too big to travel on many roads and have to be accompanied by escort cars.

这种过于庞大的卡车无法在许多道路行驶，必须由护送车押运才行，从而导致非常高昂的运输费用。

I secured additional men and resources at great personal expense.

我已经花大代价准备了额外的人马和资源。

We've just had a new garage built at great expense.

我们刚刚花了很多钱建了一个新车库。

By the end, the factory was having to fly in materials to fill urgent orders at great expense.

在工厂最后的日子里，他们不得不花高价从亚洲空运原料，以满足客户急切的订单需求。

For young people, having completed their education at great expense to their family, there is often a lot riding on their shoulders and the drive to succeed is high.

对青年人来说，已完成了伟大的教育费用对家庭，经常有很多骑着自己的肩膀和取得成功的欲望高。

Substance must always take precedence over style, but poorly presented content runs the risk of confusing the users it was meant ( often at great expense) to serve.

实质必须始终优先于形式，但是表示上欠佳的内容具有风险，可能导致用户对内容预期要达到（通常是以很大的代价）的目的感到混淆。

Other member firms picked up the offer, leaving Mizuho with a large short position that it had to unwind at great expense.

交易所其它会员公司承接了卖盘，使瑞穗证券建立了巨大的空头头寸，需要花费巨资才能平仓。

Before the health group hired advanced ICU, it had been necessary to bring in temporary doctors from out of town to staff its ICU& at great expense.

采用高级ICU公司的服务前，为了满足重症监护病房的需要，他们的医疗团队需要从外地招募临时医生，但是这样做的成本非常高。

Created at great expense the wall followed the new borders of the Ming Empire.

这座城墙沿着大明帝国的新边界，耗资巨大。

He wrote of dull-witted children educated at great expense, who "learn little more than how to carry themselves handsomely, and enter a room genteelly," but emerge "as great blockheads as ever, only more proud and self-conceited."

他写道，那些花费巨大代价在这里接受教育的蠢孩子“仅仅学会了怎样才能显得派头十足，如何彬彬有礼地进入一个房间，”但最终“还是那个榆木脑袋，只不过变得更加骄傲和自负”。

The rooms were equipped at great expense.

装备这些房间花费很高。

' Twitchers,'as enthusiasts are sometimes called, often travel long distances at great expense to catch just a glimpse of even a single rare species through their binoculars.

作为发烧友有时被称作，往往长途跋涉巨大牺牲赶上刚才看到，即使一个单一的稀有物种通过他们的望远镜。

These are things which I'm sure you can find somewhere in China, particularly in big cities like Beijing and Shanghai, but usually at great effort and expense.

而这些东西我确信你可以在中国的某些地方找到，尤其是在北京和上海这样的大城市，但是通常都很费事而且昂贵。

Most companies are keen on transforming their existing middleware to an SOA platform, often at great expense.

大多数公司热衷于将它们现有的中间件转换为SOA平台，通常这需要花费很大的代价。

It is hard to claim that pyramid-shaped tea-bags ( developed at great expense over four years) have added much to the sum of human happiness.

很难说金字塔型的袋泡茶（四年的时间花费巨大代价开发出来的）给人们增加多少的幸福。

He advance quickly in his career but only at great expense to his family.

他在职场上平步青云,但却是以家庭为代价换来的.

The data clearly show that although a few new innovations are dramatically successful, most fail, often at great expense.

统计数据清楚地表明，尽管极少数创新取得了非凡的成功，但绝大部分创新都失败了并付出惨重代价。

I arranged for you to be flown here at great personal expense.

我个人出钱安排你乘飞机来这儿。

We study at college at the great expense of our parents.

我们上大学,父母花费很大.

The garden was transformed at great expense.

花园改建花了一大笔费用。

The garden was transformed at great expense .

花园改建花了一大笔费用。